Sequential Alignment and 3rd Structure of Serine Protease Granzyme H
نویسندگان
چکیده
منابع مشابه
Nuclear targeting of the serine protease granzyme A (fragmentin-1).
Cytolytic granule-mediated target cell killing is effected in part through synergistic action of the membrane-acting protein perforin and serine proteases such as granzymes A (GrA) or B (GrB). In the present study we examine GrA cellular entry and nuclear uptake in intact mouse myeloid FDC-P1 cells exposed to perforin using confocal laser scanning microscopy, as well as reconstitute GrA nuclear...
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Generation and maintenance of protective immunological memory is the goal of vaccination programs. It has recently become clear that CD8+ memory T cells are derived directly from CTLs. The mechanisms underlying this transformation and the subsequent survival of memory cells are not completely understood. However, some effector molecules required by CTLs to eliminate infected cells have also bee...
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ژورنال
عنوان ژورنال: Pakistan Journal of Biological Sciences
سال: 2000
ISSN: 1028-8880
DOI: 10.3923/pjbs.2001.110.111